Hematology Case Studies Anemia

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Hemoglobin is contained within RBCs and is necessary to transport and deliver oxygen from the lungs to the rest of the body.

Without a sufficient supply of oxygen, many tissues and organs throughout the body can be adversely affected.

Signs and symptoms may become apparent very quickly, and the cause can be determined from a combination of physical examination, medical history, and testing. (May 2007) Genetic Home Reference: Paroxysmal Nocturnal Hemoglobinuria.

Other signs and symptoms that may develop as the anemia becomes more severe include a feeling of cold or numbness in hands and/or feet, shortness of breath, fast or irregular heartbeat, and chest pain. (December 2007) National Heart, Lung, Blood Institute: Fanconi anemia.

The patient's findings were thought to be consistent with idiopathic thrombocytopenic purpura.

In addition, the patient's microcytic hypochromic anemia, elevated RDW and decreased iron may be consistent with iron deficiency anemia in combination with blood loss. FAMILY HISTORY: The patient was born in Canada to parents of Southeast Asian descent (Thailand).A rare immature myeloid cell was seen on scanning (Figure 7).Platelets were decreased with giant forms (Figure 8).A picture of the actual cellulose acetate gel (p H 8.5) shows a prominent electro-phoretic band migrating with the hemoglobin C group (arrows, Figure 14, left).A picture of the hemoglobin electrophoresis on a citrate agar gel, p H 6.0 shows the prominent band now migrating with the Hb A group (arrows, Figure 14, right).Reticulocyte Count This test provides information on the number of relatively immature red blood cells in a person's blood sample. (February 2009) National Heart, Lung, Blood Institute: Hemolytic anemia. When someone has anemia (low RBC count, hemoglobin, and hematocrit), the results of this test can help determine the cause and/or help classify the type of anemia. (February 2009) National Heart, Lung, Blood Institute: Aplastic anemia. People with anemia may experience fatigue and weakness and may lack energy. Anemia is a fairly common condition, affecting both men and women of all ages, races, and ethnic groups. However, certain people have increased risk of developing anemia. These include people with diets poor in iron and vitamins, chronic diseases such as kidney disease, diabetes, cancer, inflammatory bowel disease, a family history of inherited anemia, chronic infections such as tuberculosis or HIV, and those who have had significant blood loss from injury or surgery.

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